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Adipokinetic Hormone II Locusta Migratoria
名称
Adipokinetic Hormone II Locusta Migratoria
分子结构式
CAS号
98968-94-6
分子式
C43H57N11O11
分子量
904.02
作用靶点
others
序列号
Pyr-Leu-Asn-Phe-Ser-Ala-Gly-Trp-NH2
短序列号
{ Pyr}-LNFSAGW-NH2
国际标识符代码
KMVRKMSUXFKTDO-UHFFFAOYSA-N
纯度
≥95%
引用文献
[1]. Oudejans RC, et al. Locust adipokinetic hormones: carrier-independent transport and differential inactivation at physiological concentrations during rest and flight. Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8654-9. [2]. Gautam UK, et al. Adipokinetic hormone promotes infection with entomopathogenic fungus Isaria fumosorosea in the cockroach Periplaneta americana. Comp Biochem Physiol C Toxicol Pharmacol. 2020 Mar;229:108677. [3]. Vroemen SF, et al. Stimulation of glycogenolysis by three locust adipokinetic hormones involves Gs and cAMP. Mol Cell Endocrinol. 1995 Feb;107(2):165-71. [4]. Goldsworthy, et al. The relative potencies of two known locust adipokinetic hormones. 1986;32(1):95-101.
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Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs)