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非天然氨基酸及其它砌块合成
Pancreatic Polypeptide (bovine)
名称
Pancreatic Polypeptide (bovine)
分子结构式
CAS号
179986-89-1
分子式
C186H287N53O56S2
分子量
4225.81
作用靶点
Neuropeptide Y Receptor
序列号
Ala-Pro-Leu-Glu-Pro-Glu-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Gln-Tyr-Ala-Ala-Glu-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
短序列号
APLEPEYPGDNATPEQMAQYAAELRRYINMLTRPRY-NH2
纯度
≥95%
引用文献
[1]. Khan D, et al. Influence of neuropeptide Y and pancreatic polypeptide on islet function and beta-cell survival. Biochim Biophys Acta. 2017 Apr;1861(4):749-758. [2]. Louie DS, et al. Action of pancreatic polypeptide on rat pancreatic secretion: in vivo and in vitro. Am J Physiol. 1985 Oct;249(4 Pt 1):G489-95.
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Pancreatic Polypeptide, bovine, a 36-amino acid, straight chain polypeptide derived primarily from the pancreas, inhibits secretin- and cholecystokinin-stimulated pancreatic secretion; Pancreatic Polypeptide, bovine acts as an agonist of NPY receptor, with high affinity at NPYR4.