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非天然氨基酸及其它砌块合成
Obestatin, human
名称
Obestatin, human
分子结构式
CAS号
1081110-72-6
分子式
C16H176N32O33
分子量
2546.89
作用靶点
others
序列号
Phe-Asn-Ala-Pro-Phe-Asp-Val-Gly-Ile-Lys-Leu-Ser-Gly-Val-Gln-Tyr-Gln-Gln-His-Ser-Gln-Ala-Leu-NH2
短序列号
FNAPFDVGIKLSGVQYQQHSQAL-NH2
国际标识符代码
IXQOGPZNKNSCJR-UHFFFAOYSA-N
溶解度
1.96mg/mL
纯度
≥95%
引用文献
[1]. Guangcai Ren, et al. Effect of TAT-obestatin on proliferation, differentiation, apoptosis and lipolysis in 3T3-L1 preadipocytes. J Pept Sci. 2013 Nov;19(11):684-91. [2]. Jian V Zhang, et al. Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake. Science. 2005 Nov 11;310(5750):996-9.
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Obestatin(human) is a 23-amino acid amidated peptide that regulates appetite and gastrointestinal motility via its interaction with GPR39. Obestatin(human) can be used for weight loss. Obestatin(human) cannot penetrate the cell membrane.