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非天然氨基酸及其它砌块合成
Gastric Inhibitory Polypeptide (1-30) (porcine)
名称
Gastric Inhibitory Polypeptide (1-30) (porcine)
分子结构式
CAS号
134875-67-5
分子式
C162H244N40O48S
分子量
3552.1
作用靶点
Insulin Receptor
序列号
Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-Arg-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys
短序列号
YAEGTFISDYSIAMDKIRQQDFVNWLLAQK
纯度
≥95%
引用文献
[1]. Krarup T, et al. Effect of porcine gastric inhibitory polypeptide on beta-cell function in type I and type II diabetes mellitus. Metabolism. 1987 Jul;36(7):677-82. [2]. G W Morrow, et al. The insulinotropic region of gastric inhibitory polypeptide; fragment analysis suggests the bioactive site lies between residues 19 and 30. Canadian Journal of Physiology and Pharmacology. January 1996. Volume 74.
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Gastric Inhibitory Polypeptide (1-30), porcine lacks the C-terminal 12 amino acid residues of natural gastric inhibitory polypeptide (GIP), exhibits biologic activity by potentiating the release of insulin and somatostatin.