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PT-141

名称
PT-141
分子结构式
CAS号
189691-06-3
分子量
1025.2
分子式
C50H68N14O10
短序列号
Ac-{Nie-Asp}-His-{D-Phe}-RWKDK
序列号
Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys -Asp-Lys
国际标识符代码
FFHBJDQSGDNCIV-MFVUMRCOSA-N
纯度
≥95%
作用靶点
Melanocortin Receptor
引用文献
[1]. Pfaus J, et al. Bremelanotide: an overview of preclinical CNS effects on female sexual function. J Sex Med. 2007 Nov;4 Suppl 4:269-79. [2]. Molinoff PB, et al. PT-141: a melanocortin agonist for the treatment of sexual dysfunction. Ann N Y Acad Sci. 2003 Jun;994:96-102.
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Bremelanotide (PT-141) is an analogue of α-melanocyte-stimulating hormone (α-MSH). Bremelanotide activates the mPOA and other hypothalamic and limbic regions of the brain involved in sexual behavior. Bremelanotide can be used for researching hypoactive sexual desire disorders.