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Propargyl-PEG2-CH2COOH

名称
Propargyl-PEG2-CH2COOH
分子结构式
CAS号
944561-46-0
分子量
202.2
分子式
C9H14O5
国际标识符代码
FWONAGPFSKACQC-UHFFFAOYSA-N
作用靶点
PROTAC Linkers
引用文献
[1]. Guangrong Zheng, et al. Compounds that induce degradation of anti-apoptotic bcl-2 family proteins and the uses thereof. WO2017184995A1.
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Propargyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Propargyl-PEG2-CH2COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.