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Exendin 4 (3-39)

名称
Exendin 4 (3-39)
分子结构式
CAS号
196109-31-6
分子量
3992.47
分子式
C176H272N46O58S
短序列号
EGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2
序列号
Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
国际标识符代码
ZCYIPGKMSDDSFW-TYVQEZQOSA-N
纯度
≥95%
作用靶点
GCGR
引用文献
[1]. David Parkes, et al. Pharmacokinetic actions of exendin-4 in the rat: Comparison with glucagon-like peptide-1. (2001), 53(4), 260–267. [2]. Affiliations, et al. GLP-1(7-36)-amide and Exendin-4 stimulate the HPA axis in rodents and humans. Endocrinology. 2010 Jun;151(6):2629-40.
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Exendin-4 (3-39) is a peptide. Exendin-4 (3-39) is a truncated form of Exendin-4 (HY-13443) that lacks the first two amino acids. Exendin-4 is a potent Glucagon-like peptide-1 receptor (GLP-1r) agonist. Exendin-4 (3-39) and Exendin-4 can be used for the research of diabetic and hypothalamic-pituitary-adrenal (HPA) axis.